Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.
Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?
Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.
The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?
A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
##首先先明確幾個概念,假藥:未拿到國傢批號進行銷售的和批準文號過期後繼續銷售的。原研藥,即指原創性的新藥,經過對成韆上萬種化閤物層層篩選和嚴格的臨床試驗纔得以獲準上市。仿製藥是指與商品名藥在劑量、安全性和效力、質量、作用以及適應癥上相同的一種仿製品。仿製藥不...
評分##藥店賣高價來研發藥,不義者用仿製藥賺錢,悲憫者用仿製藥救人,窮人用仿製藥來活命。現如今,仿製藥己不能單純用好或壞來形容,而是一個包含瞭不同人不同願望的大鍋,我隻希望都多一份寬容,藥店讓窮人活命,富人幫藥店籌款,不義者受製裁,窮人盡力幫藥店……希望一切都變好...
評分 評分##還記得兩年前上映的由徐崢等主演的那部名為《我不是藥神》的電影嗎?這部影片講述瞭神油店老闆程勇從一個交不起房租的男性保健品商販,一躍成為印度仿製藥“格列寜”獨傢代理商的故事。印度仿製的這些特效藥,能夠讓買不起天價正版藥的患者保住一綫生機,怎麼說都是在做好事、...
評分##an astonishing scandal involving people desperate for cheap drugs, "meaningless" efforts made by individuals, "evil" companies, historically do-nothing FDA, politics and poor regulations. yet sadly the same story will happen again and again and again.
評分 評分##簡直是觸目驚心的一本書,4.5星,半星給寫作的重復性打摺掉。但是看到原本應該一絲不苟的製藥業居然如此的藏汙納垢,藥性與原廠藥不能相比就不說瞭,篡改僞造數據也不說瞭,製藥環境居然如此惡劣,而廠商以及質監局的態度又是如此的nonchalant,對待監察力度很弱而便宜仿製藥需求又很大的第三世界的人命如此淡漠,相關人員隻圖暴利而不把民眾的安全和性命當一迴事,最後卻也沒有得到法律製裁的種種事情實在是讓人發指!立馬把傢長吃的藥趕快拿來查一下是不是也有質量不過關的問題。。。
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